Guadalupe is a city and surrounding municipality located in the state of Nuevo Leon, in northern Mexico. It is part of the Greater Monterrey Metropolitan area.
The municipality of Guadalupe, which lies adjacent to the east side of Monterrey, also borders the municipalities of San Nicolas de los Garza, Apodaca, Pesqueria, and Juarez. As of the 2005 census its official population was 691,434 in the city and 691,931 in the entire municipality. It is the second-largest city and municipality in the state. The municipality has an area of 151.3 km² (58.42 sq mi).
The city was founded on January 4, 1716, but the land was inhabited long before that. When Monterrey was founded in 1596, the land, which was populated by various indigenous tribes, was ceded to Diego de Montemayor, the founder of Monterrey, but he did not make use of the land.

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