Guabito is a town in the Changuinola District of the Bocas del Toro Province of Panama. Guabito is a small town located directly across the Rio Sixaola from Sixaola, Costa Rica. An elevated former railroad grade and bridge connect Guabito to Sixaola. This border crossing is popular with tourists going between Costa Rica and Bocas del Toro. Guabito is one hour ahead of Sixaola because the Costa Rica-Panama border is also a time zone boundary. Few tourists stop in Guabito longer than necessary to clear Panamanian customs.

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